Proprotein Convertase 9

A proprotein convertase that is essential for CHOLESTEROL homeostasis. It binds to and is required for the lysosomal degradation of the LDL RECEPTOR (LDLR); the VLDL receptor, and the APOLIPOPROTEIN E RECEPTOR. It also regulates neuronal APOPTOSIS.

Also Known As:

NARC-1 Protein; Neural Apoptosis-Regulated Convertase 1; Proprotein Convertase, Subtilisin-Kexin Type 9; Convertase 9, Proprotein; NARC 1 Protein; Neural Apoptosis Regulated Convertase 1; Proprotein Convertase, Subtilisin Kexin Type 9

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        Proprotein Convertase 9: 927
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        Proprotein Convertase 9: 927
      - Proprotein Convertases: 494
        Proprotein Convertase 9: 927

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Disease

Drug/Important Bio-Agent (IBA)